Senior Director, Corporate Operations

About Peptilogics

Peptilogics is a surgical therapeutics company dedicated to curing and preventing devastating medical device-related infections (MDRI). Our lead candidate, PLG0206, is a first-in-class drug that targets biofilm, a protective bacterial matrix that is the root cause of device infections across surgical categories, and has no approved cure to date. PLG0206 is currently being evaluated in a Phase 2/3 registration trial for the treatment of prosthetic joint infection (PJI), the first of multiple potential indications to treat and prevent MDRI. Job Title: Senior Director, Corporate Operations

Location(s): Pittsburgh, PA or Remote

Job Status: Full-Time

Supervisor: Chief Operations Officer (COO)

Position Overview

The Senior Director, Corporate Operations will report to the COO and play a critical role in driving the execution of Peptilogics' operational and strategic priorities. This individual will partner with executive leadership to translate business goals into actionable plans, oversee cross-functional operations, and optimize systems and processes to support growth. The Senior Director will have broad exposure across the organization, with a focus on enabling execution, improving scalability, and contributing to key strategic initiatives.

Essential Functions

Serve as a key operational leader, partnering with the COO and executive team to align strategy with execution

Lead company-wide operational planning and ensure alignment with strategic goals

Facilitate forecasts, budget development, resource allocation, vendor payments, and operational performance tracking with Finance

Implement and improve systems, processes, and tools to drive operational scalability and excellence

Implement and maintain the Quality Management System (QMS) and oversee SOP creation, updates, and audit readiness

Ensure compliance across corporate operations, development activities, legal, insurance, and regulatory requirements; foster a culture of compliance

Oversee management of non-owned physical facilities (labs, offices, external manufacturing sites), IT infrastructure, and enterprise software systems

Work closely with the Development team to manage relationships with CROs, CMOs, and preclinical and clinical trial providers

Lead sourcing, procurement, and logistics to support research, development, and external manufacturing operations

Negotiate contracts and ensure cost-effective resource utilization across all operational activities

Manage HCP contracting and compliance processes

Serve as primary point of contact for legal service vendors and coordinate legal operational needs

Identify operational risks, gaps, and bottlenecks, and proactively lead solutions

Manage the Operations team including hiring, performance, coaching, and career development

Drive operational KPIs and reporting, including preparation of materials for executive and board updates

Ensure operational compliance with company policies, regulatory requirements, and best practices

Additional Duties and Responsibilities

Support business development and partnership activities through operational due diligence and integration planning

Support fundraising and investor relations by providing operational insights, data, and reporting

Support cross-functional teams (R&D, Commercial, Project Management) in executing strategic initiatives

Collaborate with the COO and Finance on long-range planning and scenario modeling

Contribute to shaping company culture by supporting initiatives around collaboration, communication, and team building

Perform other duties as assigned

Required Qualifications and Skills

Bachelor's degree in a relevant field (e.g., life sciences, business, engineering); advanced degree (MBA, MS, PhD) preferred

10+ years of experience in biotech, pharmaceutical, or life sciences operations

3–5 years in a leadership or senior operations role, ideally in a high-growth or venture-backed environment

Experience scaling operations in a startup or growth-stage company (preferred)

Prior operational involvement in fundraising, investor relations, or board reporting (preferred)

Strong project management and organizational skills, with the ability to manage complex, cross-functional initiatives

Excellent financial and business acumen; experience with budgets, forecasts, and KPIs

Proven ability to build, lead, and develop teams

Deep understanding of operational compliance, including legal, regulatory, quality management (QMS), and audit readiness

Proven ability to build, lead, and develop teams across diverse operational functions

Exceptional interpersonal and collaboration skills, with the ability to influence at all levels

Outstanding verbal and written communication skills, including executive-level reporting and presentations

Excellent verbal and written communication skills, including executive-level reporting and presentations

Ability to thrive in a dynamic, fast-paced environment with shifting priorities

Ability to drive cross-functional alignment and collaboration across scientific, operational, and corporate teams

Strategic thinking and ability to scale operations in a growth-stage environment or commercialization-ready biotech environment

Experience with contract development, procurement, and resource optimization

Familiarity with QMS implementation, SOP development, and compliance frameworks in a biotech/pharma setting

Financial fluency to support investor relations, board reporting, and fundraising activities

Familiarity with technology-driven R&D environments including computational biology, machine learning

Change management and process improvement capabilities

Experience managing HCP engagement processes and ensuring compliance in clinical development

Our Commitment to Equal Opportunity

Peptilogics is proud to be an equal opportunity employer. We make hiring decisions based on qualifications, experience, and potential—without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other protected status. We welcome candidates from all backgrounds to apply.